EXCLUSIVE: Mos Def has joined HBO’s upcoming Mike White/Laura Dern comedy series Enlightened as a regular. The single-camera comedy stars Dern as a self-destructive woman who has a spiritual awakening and decides to live an enlightened life, which creates havoc at home and work. Mos Def will play her new boss when she returns to work. This marks Mos Def’s first full-time series gig. He recurred on Comedy Central’s Chapelle’s Show and recently did a memorable guest stint on Fox’s House. At HBO, he starred in the 2004 movie Something the Lord Made, which earned him an Emmy nomination.