ITV has set the roster for its upcoming four-part miniseries that follows the lives and loves of both historical and fictional characters in 1666 London as The Great Fire rages. Broadchurch‘s Andrew Buchan, Rose Leslie (Utopia, Game Of Thrones, Downton Abbey), Jack Huston (American Hustle, Boardwalk Empire) and Daniel Mays (Mrs Biggs, Welcome To The Punch) have each taken on key roles in the production from Fleming and Mistresses‘ Ecosse Films. Inspired by the real events of 1666 when nearly half of London was destroyed in less than a week, the drama is written by Tom Bradby, political editor of ITN and author of Shadow Dancer. The story unfolds over four consecutive days as the fire takes hold of the city and the people desperately attempt to overcome the flames amid a threat to the monarchy. Buchan will play humble baker Thomas Farriner in whose shop the fire began on September 2, 1666. Leslie plays his sister-in-law with whom he has a complex relationship. Huston is the playboy King Charles II and Mays is Samuel Pepys, a close confidante. Per ITV, pyrotechnics and special effects, as opposed to CGI, will create the fire sequences as London burns. Also in the cast are Charles Dance (Game Of Thrones), Oliver Jackson-Cohen (Dracula), Andrew Tiernan (Ripper Street), David Schofield (Da Vinci’s Demons), Sonya Cassidy (Vera) and Perdita Weeks (The Invisible Woman). Shooting is due to start this month in London, Kent, Surrey and Oxfordshire. Douglas Rae and Lucy Bedford are exec producing for Ecosse; Gina Cronk (The White Queen) is producing and Jon Jones (Lawless, Rogue, Mr Selfridge) is directing. Chris Hurford and Tom Butterworth (Doc Martin, Ashes To Ashes) wrote one of the episodes. ITV Studios Global Entertainment is distributing intenrationally with a kickoff at Mip-TV next month.