BREAKING….Anne Fletcher is set to direct Murder Mystery, a whodunit action comedy written by The Amazing Spider-Man scribe James Vanderbilt. TWC-Weinstein and Endgame are teaming on the pic, about a married couple who takes the honeymoon they never had in hopes of saving their struggling marriage but soon find themselves in the middle of their very own murder mystery when one of their fellow cruise passengers is found dead. Beau Flynn and Tripp Vinson are producing along with Vanderbilt, Endgame’s James D. Stern and Charlize Theron via her Denver and Delilah Productions. Endgame’s Douglas E. Hansen, Tower Hill’s William Shively and Denver and Delilah’s Beth Kono and A.J. Dix will executive produce. Denver and Delilah had originally set John Madden to helm the pic back in 2012, with Theron at the time in talks to star as well. “Murder Mystery is a throwback to Agatha Christie novels with a comedic spin. We have been huge fans of Anne Fletcher for years and have wanted to work with her. This film seems like the perfect project to team up with Anne, Endgame and Tripp,” said Bob Weinstein and Harvey Weinstein, co-chairmen of The Weinstein Company.

Overseeing production for TWC-Dimension are SVP Production and Creative Affairs Matthew Signer and VP Production and Development Keith Levine; President of Production Julie Goldstein and SVP Development Lucas Smith Sr oversee for Endgame. The deal was negotiated for TWC-Dimension by Phillip Muhl, President Business and Legal Affairs, nad for Endgame by Greg Schenz.

The Weinsteins launched their TWC-Weinstein label less than two weeks ago for Harvey and Bob Weinstein to team on films for which they share a common passion. The first title is Paddington, the upcoming big-screen transfer of Michael Bond’s classic kids character Paddington Bear with Colin Firth and Nicole Kidman among the big names attached.

Fletcher (The Proposal, 27 Dresses) is repped by UTA and attorney David Webber. Vanderbilt is repped by WME, Fuse Creative Management and McKuin Frankel Whitehead. Theron is repped by WME.