Michelle Monaghan rounds out the lead cast of Open, HBO’s drama pilot from Ryan Murphy. The Fox 21 project, which Murphy co-wrote with Lauren Gussis, is described as a modern, provocative exploration of human sexuality and relationships. Monaghan will play the central female character Grace, a successful and recently engaged gynecologist. She joins Scott Speedman, who plays Grace’s fiance Jonathan, Wes Bentley (Evan), Anna Torv (Windsor) and Jennifer Jason Leigh (Holly). Open keeps Monaghan — repped by ICM Partners, Circle of Confusion, and attorney Robert Offer — in the HBO fold. She plays the female lead opposite Matthew McConaughey and Woody Harrelson in the pay cable network’s eight-episode limited series True Detective, which premieres in January 2014. Her upcoming features include Fort Bliss, A Many Splintered Thing and Better Living Through Chemistry.