Universal Pictures‘ Despicable Me 2 continues to rake it in around the world. The animated sequel surpassed the $800 million mark today with Friday’s estimated domestic grosses of $349.9 million and $451.4 million international bringing the worldwide take to $801.3 million. The Universal and Illumination Entertainment pic has opened at #1 in 45 territories and is the second highest grossing pic of 2013 worldwide behind Iron Man 3. Domestically it’s #2 and internationally only third behind Iron Man 3 and Fast & Furious 6. Last month NBCUniversal chief Steve Burke declared Despicable Me 2 the studio’s most profitable film in history; it’s also Uni’s second highest grosser of all time worldwide behind Jurassic Park.