There will be a recasting on the newly picked up NBC multi-camera comedy series Sean Saves The World. Lindsay Sloane, who co-starred opposite Sean Hayes in the pilot, will be departing. Written by Fresco and directed by James Burrows, the comedy, from Universal TV and Hazy Mills, centers on Sean (Hayes), who must figure out how to parent his 14-year-old daughter (Samantha Isler), who just moved in, while navigating a temperamental new boss (Thomas Lennon) at work. Sloane played Liz, Sean’s long-time loyal friend, a former therapist, with whom he also works. This marks the second recasting on a newly picked up series, joining another NBC comedy, The Family Guide, which is subbing Parker Posey.