EXCLUSIVE: Matt Letscher is set to co-star and Sigourney Weaver to guest star in HBO’s comedy pilot Spring/Fall, starring Tea Leoni and Hope Davis and directed by Jake Kasdan. Set in New York City against the backdrop of the fashion world, the project centers on the dysfunctional partnership between Margo (Leoni) and Eden (Davis), two women with different approaches to career, family and friendship. Letscher will play Margo’s ex-husband. In a rare series appearance, Weaver will play a meticulously dressed, authoritative fashion editor. Also cast in the pilot are Jason Antoon as Eden’s current best friend; Marin Hinkle as Eden’s sister; and Jessica Hecht as Margo’s best friend, a successful management consultant. Letscher, repped by IFA and Sanders.Armstrong.Caserta, recently recurred on HBO’s Entourage.

Ana Alexander (Cinemax’s Femme Fatales), Chad Everett (Melrose Place) and Sally Kellerman (90210) have been cast in Cinemax’s 13-episode late-night half-hour dramedy Chemistry, which centers on the complexity of the relationship between Liz (Alexander) and Michael (Jonathan Chase), who have strong physical attraction bordering on erotic madness. Everett will play Michael’s father, a successful entrepreneur and playboy; Kellerman will play a close friend of Liz who has had a storied past of famous conquests.