EXCLUSIVE: Jillian Bell is attached to star as the titular character in Brittany Runs a Marathon, with Michaela Watkins (Casual), Utkarsh Ambudkar (White Famous), Lil Rel Howery (Get Out), Micah Stock and Alice Lee rounding out the cast. The indie film marks the debut for director Paul Downs Colaizzo, who came up with the original idea the film based on. Material Pictures’ principals Tobey Maguire and Matthew Plouffe are producing the project with Picture Films’ Margot Hand.

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Inspired by the journey of Colaizzo’s real-life friend, The pic follows an underachieving and over-partied 28-year-old woman who decides to take control of her life— one New York City block at a time.

Richard Weinberg, Bell and Colaizzo serve as executive producers for the film, which is in production. Endeavor Content will handle worldwide sales for the film.

Bell recently showcased her comedy muscles in films such as Rough Night opposite Scarlett Johannsson and Kate McKinnon, New Line’s Fist Fight with Charlie Day and Ice Cube and Paramount’s Office Christmas Party with Jason Bateman and Jennifer Aniston. Among her upcoming projects is the Splash remake opposite Channing Tatum, which was picked up by Disney with Imagine Entertainment producing. She’s repped by UTA and 3 Arts Entertainment.

Watkins is repped by Haven Entertainment, UTA & Patti Felker; Ambudkar is with Gersh and 3 Arts;  Howery is repped by UTA and 3 Arts Entertainment; and Stock is with  ICM and Anonymous Content.