Jimmy Kimmel Live again will join forces with Bono and RED for a special episode of the ABC late-night show to raise money and awareness in the fight against AIDS. Julia Roberts, Channing Tatum, Kristen Bell, DJ Khaled, Neil Patrick Harris, Halsey and the Killers are booked to participate in the November 22 edition of the show.

The broadcast will kick off the second annual RED Shopathon, featuring limited edition (RED) products as well as experiences with celebrities via Omaze. World AIDS Day is December 1.