EXCLUSIVE: Reese Witherspoon and Bruna Papandrea, who co-founded and co-ran the production company Pacific Standard that produced such hits as David Fincher’s Gone Girl and the Jean-Marc Vallee-directed Wild, are ending their long partnership.

Papandrea will be leaving to start a new venture. Witherspoon will retain control of Pacific Standard, and the duo will continue to produce the projects they have in development together including Luckiest Girl Alive at Lionsgate/Summit, All Is Not Forgotten at Warner Bros, and Ashley’s War at Fox 2000. They also have the upcoming HBO mini Big Little Lies which stars Witherspoon, Nicole Kidman, Shailene Woodley, Zoe Kravitz and Laura Dern. They also will continue to work together under Pacific Standard’s overall deal at ABC. At a time when books often get short shrift as source material, Witherspoon and Papandrea have shown they can be a gold mine and that emphasis put them on the ground floor of strong projects from Gone Girl to Wild and Big Little Lies.

“I’m very proud of the projects that Bruna and I have produced together,” said Witherspoon. “Bruna is a hard-working, extremely talented producer. I’m happy to further collaborate with her on the strong slate of Pacific Standard properties.”

Said Papandrea: “It’s been an amazing 5 years with Reese. I’m so proud of what the two of us have created together. She’s such a talented and inspiring producing partner and I’m really excited that we’ll continue to collaborate on our many terrific on-going projects.”