Sagan Lewis, a co-star on NBC medical drama St. Elsewhere and wife of Emmy-winning TV creator Tom Fontana, died of cancer Sunday at her home in New York City, according to UTA. She was 63.

The Omaha, Nebraska native began her acting career in the late 1970s. She was auditioning for the acting company at the Williamstown Theatre Festival in 1978 when she met her future husband Fontana, who at the time was an aspiring writer and assistant to the festival’s artistic director. They moved to Los Angeles in 1980 where Fontana became a writer on NBC medical drama, St. Elsewhere, and Lewis took on a co-starring role on the series. She went on to play Dr. Jacqueline Wade on the show for seven seasons.

From that role, Lewis went on to appear in television movies such as Full Ride and Cocaine: One Man’s Seduction, and played Judge Susan Aandahl in multiple episodes of Fontana’s Emmy-winning NBC series Homicide: Life on the Street. She appeared in the final half hour of “M*A*S*H” as well.

Lewis and Fontana divorced in 1993, but later remarried in 2015.

Lewis is survived by her husband Tom Fontana, her son Jade Scott Lewis, and sisters Robin Schultz and Laurie Rittenbach as well as brothers James Paul Lewis, John Mickey and Joseph Mickey. Her elder brother Tom Lewis died in 2011 of brain cancer.

Contributions can be made to The Ocean Foundation.