We’re getting the first look at Showtime’s Masters of Sex Season 4 ahead of its September 11 premiere, along with newly released key art (below).

Masters of Sex Season 4 Key Art 1
Showtime

Michael Sheen and Lizzy Caplan star as real-life pioneers of human sexuality, William Masters and Virginia Johnson. Season four begins in 1968 and will take viewers into the “swinging ‘70s,” during which time the series’ characters will take on new partners both professionally, personally and sexually. Beginning the season at odds and burdened by lies, the pair slowly switch rores in both their work and the bedroom.

Guest stars include Beau Bridges, Sarah Silverman, Niecy Nash, Betty Gilpin, Andre Royo, David Walton, Alysia Reiner, Jeremy Strong and Ashley Zukerman.

Masters of Sex was developed for television by Michelle Ashford (The Pacific), who also serves as an executive producer, along with Sarah Timberman, Carl Beverly, Amy Lippman and Judith Verno. Michael Sheen, Lizzy Caplan, Tammy Rosen and Thomas Maier serve as producers. Produced by Sony Pictures Television, Masters of Sex is an adaptation of Thomas Maier’s book Masters of Sex: The Life and Times of William Masters and Virginia Johnson, The Couple Who Taught America How To Love.

Check out the clip above.