Will & Grace alumna Megan Mullally and Nick Offerman (Parks & Recreation) will guest star in Season 2 of CBS comedy series Life In Pieces.

The real-life couple will play a brother-sister duo who are parents to Clementine, played by Hunter King. “Hunter’s character calls Nick’s character (Spencer) “Uncle Dad.” He’s helped his sister raise her children. They have a really unique relationship,” said Life In Pieces creator Justin Adler during a TCA lunch for the show.

Mullally’s character is Mary-Lynn, Clementine’s (King) free spirited, and very open minded mother. Her husband left her soon after Clementine was born, so she asked her brother to step in and be “Uncle Dad.” Mary-Lynn and Spencer (Offerman) are very supportive and caring parents to Clementine, but their relationship with each other is a little too close for comfort. In fact as adult siblings they share a bedroom with twin beds.

Life in Pieces is a comedy about one big happy family and its sometimes awkward, often hilarious and ultimately beautiful milestone moments as told by its various members.

Mullally and Offerman are both repped by UTA.

Life In Pieces is produced by Twentieth Century Fox Television. The second season premieres Thursday, October 27 on CBS.