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Netflix has set the cast of Friends from College, a new 8-episode comedy series from Nick Stoller (Neighbors) and Francesca Delbanco. Key & Peele star Keegan-Michael Key is returning to primetime, toplining the series, which also has cast How I Met Your Mother alumna Cobie Smulders, Annie Parisse (Vinyl), Nat Faxon (Married), Fred Savage (The Grinder) — reuniting with The Grinder executive producer Stoller — and Jae Suh Park (The Mindy Project).

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The show centers on a group of friends who went to Harvard together and are now facing down their forties and experiencing a range of success, or lack thereof, both professionally and domestically. With interwoven and oftentimes complicated relationships with one another, the series is a comedic exploration of old friendships, former romantic entanglements and balancing adult life with nostalgia for the past.

The husband and wife duo of Stoller and Delbanco — who both attended Harvard — will serve as executive producers and writers on the series and Stoller will direct all eight episodes. Production will begin this fall in New York.

“Nick is a comedic mastermind. With Friends from College, he and Francesca have created a world that is both moving and very, very funny,” said Cindy Holland, Netflix VP of Original Content.

Stoller recently directed the comedy feature Neighbors and its sequel Neighbors 2: Sorority Rising. He is currently working on the the upcoming animated film Storks for Warner Brothers. For TV, Stoller co-wrote and is an executive producer working on the third season of The Carmichael Show.

Parisse is repped by Gersh.