Keesha Sharp, who plays attorney Johnnie Cochran’s wife Dale in the hit FX miniseries American Crime: The People vs. OJ Simpson, is set to co-star opposite Damon Wayans Sr. in Lethal Weapon, Fox’s hourlong pilot based on the hit buddy cop action comedy movie franchise. Girlfriends alumna Sharp, who will play one of the lead female roles, Trish, replaces fellow former Girlfriends star Golden Brooks, who was originally cast in the part. The decision was made after the project’s table read last night.

In Fox’s Lethal Weapon, written by Matt Miller and directed by McG, when Texas cop and former Navy SEAL Martin Riggs (Clayne Crawford) suffers the loss of his wife and baby, he moves to Los Angeles to start anew. There, he is partnered with LAPD detective Roger Murtaugh (Wayans), who, having recently suffered a “minor” heart attack, must avoid stress in his life.

Sharp will play Roger’s hardworking, perceptive and loving wife Trish, who worries about him and is not thrilled when she hears about his new adrenaline-crazed partner. In the movies, Trish was played by Darlene Love and Roger by Danny Glover.

Miller, McG, Dan Lin and Jennifer Gwartz executive produce the pilot for Warner Bros. TV and Lin Pictures.

Sharp, who also co-starred on the TBS comedy Are We There Yet, will next be seen recurring on the CW’s Significant Mother. She is repped by Genesis Entertainment and Abrams Artists Agency.