A24 has dropped the first trailer for Anna Boden and Ryan Fleck’s gambling road trip pic Mississippi Grind. Newly minted Emmy nominee Ben Mendelsohn (Netflix’s Bloodline) stars as Gerry, a down-on-his-luck gambler whose fortunes begin to change when he meets Curtis (Ryan Reynolds), a younger, charismatic poker player. The two bond and head out on a road trip down the Mississippi River to a legendary high-stakes poker game in New Orleans, hitting just about every bar, racetrack, casino and pool hall along the way.

Sienna Miller, Analeigh Tipton, Robin Weigert, and Alfre Woodard also star. It is produced by Jamie Patricof and Lynette Howell, who previously worked with Fleck and Boden on Half Nelson. A24 picked up the rights following the film’s premiere at Sundance and will release in conjunction with DirecTV. It hits theaters on September 25 and will be available on DirecTV August 13. Check it out above.