Broad Green Pictures is teaming with Charlize Theron’s Denver & Delilah and Foundation Features to produce and finance Brain On Fire, the film based on Susannah Cahalan’s bestselling memoir. Chloë Grace Moretz has been tapped to play the lead role of a young woman’s terrifying descent into insanity. When Denver & Delilah acquired rights to the book back in May 2014, it had Dakota Fanning attached.

Gerard Barrett (Glassland) will direct the pic, which still co-stars Jenny Slate and Thomas Mann. Principal photography now begins July 13 in Vancouver and the film is set for release in 2016. Theron, A.J. Dix and Beth Kono of Denver & Delilah, and Rob Merilees and Lindsay Macadam of Foundation Features are producing.

Broad Green will distribute Brain on Fire in the U.S., while studio partner Mister Smith Entertainment will continue to sell international rights after launching the film at Berlin’s EFM in February.

Brain On Fire follows Cahalan (Moretz), a rising journalist at the New York Post who mysteriously starts having seizures and hearing voices. As weeks go by and she rapidly descends into insanity, she moves inexplicably from violence to catatonia. Following a series of outbursts, misdiagnoses and a prolonged hospital stay, a lucky last-minute intervention by one doctor finally gives her a diagnosis and hope to rebuild her life.

“We are excited to work with this incredible group of filmmakers and actors to bring Susannah Cahalan’s life story to the big screen,” said Broad Green Pictures’ chief creative officer Daniel Hammond. “With the help of our partners at Mister Smith, we will be able to share this incredibly moving film with a global audience.”

The deal was brokered on behalf of the filmmakers by WME Global, with Broad Green repped by production president Victor Moyers, EVP Legal & Biz Affairs and General Counsel Chris Tricarico.