American Horror Story meets Glee. In their first big programming move at Fox, Fox TV Group chairmen Dana Walden and Gary Newman have given a 15-episode straight-to-series order to one of their most trusted creators at 20th Century Fox TV, Ryan Murphy. With Glee wrapping its run on Fox, the network has ordered comedy-horror anthology Scream Queens, from Glee creators Murphy, Brad Falchuk and Ian Brennan. This marks the second straight-to-series order for an anthology series for Murphy and Falchuk on the heels of FX greenlighting an American Crime Story spinoff from the duo’s hugely successful horror anthology series American Horror Story.

The first installment of Scream Queens, created by Murphy, Falchuk and Brennan, revolves around a college campus which is rocked by a series of murders. 20th Century Fox Television and Murphy’s studio-based Murphy Television produce, with Murphy, Falchuk, Brennan and Dante Di Loreto executive producing.

“I knew I wanted to work with Brad and Ian again on something comedic, and we are having a blast writing Scream Queens,”said Murphy who revealed details about the setup of the series. “We hope to create a whole new genre – comedy-horror – and the idea is for every season to revolve around two female leads. We’ve already begun a nationwide search for those women, as well as 10 other supporting roles, and we’re very grateful to Dana and Gary for their enthusiastic support.”

Longtime 20th TV toppers Walden and Newman said that getting a new series created by Murphy on Fox was a top priority in their first season overseeing the network as they’re focused on rebuilding a lineup that has floundered in the ratings.  “We loved every element of the pitch for this show — the genre-bending concept, which blends true horror with big comedic moments; the diverse and unforgettable characters and reuniting the phenomenal creative team that delivered Glee,” they said, adding that the straight-to-series order is “a huge commitment and an expression of our faith in Ryan.”