EXCLUSIVE: Natalie Dormer has been set to star in Patient Zero, the Screen Gems action thriller that Stefan Ruzowitzky will direct from a script written by Mike Le. Vincent Newman is producing. Dormer has been building feature credits that include The Hunger Games: Mockingjay Parts 1 & 2, Rush and Captain America: The First Avenger. She is best known for playing Margaery Tyrell, whose short reign as queen on HBO’s Game Of Thrones was interrupted when the tyrant king Joffrey was poisoned during their wedding reception.

joffrPatient Zero focuses on an unprecedented global pandemic that causes the evolution of a new species. An aggressive form of rabies turns the infected into predators, addicted to violence. An inexplicably gifted human survivor with the ability to speak the new mutant language leads a hunt for Patient Zero and hope for a cure.

Dormer is repped by UTA, Untitled Entertainment, attorney Karl Austen and United Agents in the UK.