Comic-Con-goers got a glimpse of Guillermo del Toro‘s animated The Book Of Life at Fox’s panel last month, and now the official trailer has dropped. A romantic adventure inspired by the Mexican Day of the Dead holiday, it centers on Manolo (Diego Luna), who must fight for his lady love when spirits La Muerte (Kate del Castillo) and Xibalba (Ron Perlman) meddle in the world of the living. Christina Applegate, Ice Cube, Hector Elizondo, Zoe Saldana, Channing Tatum also are among the killer voice cast in director Jorge R. Guiterrez’s film. Fox opens it wide October 17: