Twins Maggie and Milo have been estranged for a decade, but a surprise reunion has them re-examining their lives and relationship in this R-rated dramedy. Longtime Saturday Night Live colleagues Kristen Wiig and Bill Hader star as the titular sibs in The Skeleton Twins, which won the Waldo Salt Screenwriting Award for Craig Johnson and Mark Heyman. Johnson also directed. Luke Wilson, Ty Burrell and Boyd Holbrook co-star. Lionsgate and Roadside Attractions will open the film, which counts the Duplass brother among its exec producers, in theaters on September 19 — the same day fellow SNL veteran Tina Fey’s This Is Where I Leave You bows wide. Here’s a look: