Rachael Harris has landed a co-starring role opposite Ben Falcone in CBS’ untitled multi-camera comedy written by Falcone and fellow actor Larry Dorf and co-executive produced by Falcone’s wife, Mike & Molly star Melissa McCarthy. The project centers David (Falcone), a single 37-year-old who loses everything he has in the real estate collapse and finds himself back home in the house he grew up in … with his parents. Harris will play his frazzled sister who has three kids. Warner Bros TV is producing.

James Carpinello and Jesse Lee Soffer have been cast in Fox’s untitled Josh Berman/Rob Wright medical drama pilot, about a female doctor working for the mob in Chicago. As The World Turns alum Soffer, repped by Innovative and The Collective,  will play her brother. Carpanello, repped by APA and Untitled, will play a mid-level member of the Southside Outfit. He recently recurred on CBS’ The Good Wife and just wrapped Gangster Squad. Michael Dinner is directing the project, produced by Sony Pictures TV.