Jennifer Aniston, Alicia Keys, Demi Moore and Patty Jenkins have signed on to direct the Lifetime original movie Project Five, an anthology of five short films exploring the impact of breast cancer on people’s lives.  Aniston, Marta Kauffman, Paula Wagner, Kristin Hahn, Kevin Chinoy and Francesca Silvestri will executive produce the movie, which reunites former Friends star Aniston and co-creator/executive producer Kauffman  for the first time since the end of the hit NBC series. Sony Pictures TV is producing.

Kauffman developed the interconnected story arc of Project Five, which will mix drama and comedy to explore the effect that breast cancer and its diagnosis have on women and their relationships. The five short films in Project Five were written under Kauffman’s supervision by Stephen Godchaux (Spin City), Jill Gordon (Cupid), Howard Morris (Women are Crazy), Deirdre O’Connor (The Electric Company) and Wendy West (Dexter). Aniston, Keys, Moore and Jenkins will each direct one short, with a fifth director expected to be announced soon. “Our hope with Project Five is to entertain, inform and inspire dialogue, research and prevention,” Aniston said. “Otherwise, our goals are small — we want these films to move people and empower those affected by breast cancer to stand tall through this challenge, which impacts ALL of our lives, no matter who we are.”